DRUG VERSUS DIETARY SUPPLEMENT
What happens to Drugs and/or Nutritional Supplements after ingestion?
- DRUG: In pharmacology, a drug is defined as “a chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well-being.” Drugs may be prescribed for a limited duration, or on a regular basis for chronic disorders.
- DIETARY SUPPLEMENT: Congress defined the term “dietary supplement” in the Dietary Supplement Health and Education Act (DSHEA) of 1994.
- A dietary supplement is a product taken by mouth that contains a “dietary ingredient” intended to supplement the diet. The “dietary ingredients” in these products may include: vitamins, minerals, herbs or other botanicals, amino acids, and substances such as enzymes, organ tissues, glandulars, and metabolites.
- Dietary supplements can also be extracts or concentrates, and may be found in many forms such as tablets, capsules, softgels, gelcaps, liquids, or powders. They can also be in other forms, such as a bar, but if they are, information on their label must not represent the product as a conventional food or a sole item of a meal or diet.
- Whatever their form may be, DSHEA places dietary supplements in a special category under the general umbrella of “foods,” not drugs, and requires that every supplement be labeled a dietary supplement.
- Drugs and supplements can be ingested in several types formulations
- Type of formulations
- Listed in order of how fast they are absorbed into the blood stream
- This applies to
- Capsules: must disintegrate or open to release the drug and/or supplement
- Softgels: The gelatin coating must disintegrate to release the drug and/or supplement.
- Tablets: must disintegrate (break apart) into small particles
- After the drug is disintegrated it must dissolve in the gastrointestinal fluid before it can be absorbed into blood stream.
- This applies to:
- Suspensions: Suspensions are drugs/supplements particles suspended in a fluid. They do not dissolve in this fluid.
- Capsules: The disintegrated capsule must dissolve.
- Tablets: The disintegrated tablet must dissolve.
- Bio-availability of a drug and/or supplement is the percentage/amount of the drug that reaches the blood stream.
- Many factors affect this most important pharmacokinetic process including:
- The drug or supplement itself
- Individual or patient specific factors
- Disease conditions
- And many more
- Once absorbed into the blood stream the drug or supplement must pass through the liver where it may undergo metabolism.
- The liver converts some drugs or supplements into active and/or inactive metabolites.
- Depending on the drugs or supplements some metabolites may be toxic to the body and to the liver itself, kidneys, and other vital organs.
- Some drugs or supplements inhibit the liver function while others stimulate the liver function.
- Inhibition of liver function can cause higher levels of drug than intended which may harm you.
- Stimulation of liver function can cause lower levels of drug than need to be effective.
- Once a drug or supplement passes through the liver, it must now travel to its intended target organ and bind to receptors in the organ in order to produce its effect.
- Some drugs or supplements compete for the same receptor site. Therefore if you use two of more competing drugs, they may cancel out each other’s effect or one will not work.
- More is NOT better because there is a limited number of receptor site. Using just the right amount of drug is therefore very important.
- Remember that some drug metabolites may be toxic, therefore, the more drug you have in your system, the more toxic metabolite you may also have to affect your vital organs.
- Once a drug or supplement has done its job, it must be eliminated from the body.
- Some drugs or supplements are eliminated via the kidney, liver, feces, and various body fluids.
- Depending on the drug supplement, if it is not eliminated at the right time, it can further damage organs.
- For example, if the drug or supplement is eliminated via the kidney and you have a kidney disease, the kidney will not be able to eliminate the drug leading to accumulation of the drug in the body.
- TO THE BODY, THERE IS NO DIFFERENCE BETWEEN A DRUG AND A SUPPLEMENT
- USE PREMIUM PRODUCTS DESIGNED BY REPUTABLE A COMPANY OR A KNOWLEDGEABLE HEALTH CARE PROFESSION
- ASK IF THE PRODUCT DEVELOPER USES HIS/HER OWN PRODUCT; AND IF SO DOES HE/SHE LOOK LIKE WHAT THE LABEL SAYS
- KNOW WHAT YOU PUT IN YOUR BODY
- READ PRODUCT LABEL CAREFULLY
- IF YOU DON’T NEED IT, DON’T USE IT AND IF YOU NEED IT, KNOW WHY
- IF YOU USE IT, USE JUST THE RIGHT AMOUNT
- “MAY YOU LIVE LONG AND HEALTHY”
- “SCULPT YOUR MASTERPIECE”™
Disclaimer: This information is provided for informational purposes only, and is not meant to be a substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or for prescribing any medication or dietary supplement. You should carefully read and follow all product packaging and labeling instructions. You should consult with a health care professional before starting any diet, exercise, or supplement program. If you have or suspect that you have a medical problem, promptly contact your health care provider. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. KOFLEX SPORTS NUTRITION is not responsible for typographical errors.